六合彩论坛

作者：2017-07-03浏览次数：20733

徐 标

博士研究生导师简介

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, ;,  ,  ,  ,  ,  ,  ,  .Meta-Analysis Comparing Results of Transcatheter Versus Surgical Aortic-Valve Replacement in Patients WithSevereAortic Stenosis. Am J Cardiol. 00:1−10

  • , , ,  ,  ,  ,  ,  ,  , , ,  .Long non-coding RNA MEG3 knockdown attenuates endoplasmic reticulum stress-mediated apoptosis by targeting p53 following myocardial infarction. J Cell Mol Med. 2019 Dec;23(12):8369-8380.

  • ,  ,  , ,  ,  ,  , . Treatment of refractory ventricular tachycardia with combination of alcohol ablation and radiofrequency ablation. J Geriatr Cardiol.. 2019 Aug;16(8):660-662.

  • ,  ,  , , , ,  , ,  . PM2.5 promotes plaque vulnerability at different stages of atherosclerosis and the formation of foam cells via TLR4/MyD88/NFκB pathway. Ecotoxicol Environ Saf. 2019 Jul 30;176:76-84.

  • , , , , , , ,  .LIM kinase 1 acts as a profibrotic mediator in permanent atrial fibrillation patients with valvular heart disease. J Biosci. 2019 Mar;44(1). pii: 16.

  • ,  ,  , , , , ,   Combined Primary PCI with Multiple Thrombus Burden Reduction Therapy Improved Cardiac Function in Patients with Acute Anterior Myocardial Infarction. Int Heart J. 2019 Jan 25;60(1):27-36.

  • , , ,  ,  ,  ,  , ,  ,  ,  . Identification of the potential therapeutic target gene UBE2C in human hepatocellular carcinoma: An investigation based on GEO and TCGA databases. Oncology Letters. 2019;17(6):5409-5418.

  • , , , , and .Resveratrol Improves Tube Formation in AGE-Induced Late Endothelial Progenitor Cells by Suppressing Syndecan-4 Shedding. . 2018; 2018: 9045976.

  • Jun X, Jin G, Fu C, Jinxuan Z, Xuelin L, Jiaxin H, Shuaihua Q, Anqi S, Jianzhou C, Lian Z, Xiwen Z, Baoli Z, Biao X.PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice.  2018 Aug;104:550-557. 

  • Wei ZH, Dai Q, Wu H, Song J, Wang L, Xu B.Takotsubo cardiomyopathy after pacemaker implantation. J Geriatr Cardiol. 2018 Mar;15(3):246-248.

  • Wang K, Shen Y, Li PW, Gu R, Zhang JM, Wang L, Bai J, Xu B. ST-Segment Elevation Myocardial Infarction Patients Complicated by Out-of-Hospital Cardiac Arrest May Not Benefit from Emergency Percutaneous Intervention. Chin Med J (Engl). 2018 Mar 20;131(6):746-747.

  • Zhang XL, Kang LN, Wang L, Xu B.Percutaneous closure versus medical therapy for stroke with patent foramen Ovale: a systematic review and meta-analysis.BMC Cardiovasc Disord. 2018 Mar 2;18(1):45.

  • Zhang XW, Zhang XL, Xu B, Kang LN.Comparative safety and efficacy of insulin degludec with insulin glargine in type 2 and type 1 diabetes: a meta-analysis of randomized controlled trials.Acta Diabetol. 2018 May;55(5):429-441.

  • Hu L, Yao X, Huang H, Guo Z, Cheng X, Xu Y, Shen Y, Xu B, Li D.Clinical significance of germline copy number variation in susceptibility of human diseases.J Genet Genomics. 2018 Jan 20;45(1):3-12.

  • Di W, Lv J, Jiang S, Lu C, Yang Z, Ma Z, Hu W, Yang Y, Xu B.PGC-1: The Energetic Regulator in Cardiac Metabolism.Curr Issues Mol Biol. 2018 Feb 1;28:29-46.

  • Qing Dai, Jie Song, Jian He, Biao Xu.Rare Case of Anomalous Original Left Circumflex Artery Stenosis After Artificial Mitral Valve Replacement. JACC: Cardiovascular Interventions. 2017 Apr 10;10(7):e71-e73.

  •  Xin-Lin Zhang, Qing-Qing Zhu, Jing-Jing Yang, Yu-Han Chen, Yang Li, Su-Hui Zhu, Jun Xie, Lian Wang,Li-Na Kang and Biao Xu.Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis. BMC Medicine.2017 Apr 21;15(1):84.

  •  Xinlin Zhang, Jun Xie, Suhui Zhu, Yuhan Chen, Lian Wang, Biao Xu.Next-generation sequencing identifies pathogenic and modifier mutations in a consanguineous Chinese family with hypertrophic cardiomyopathy. Medicine. 96(24): p. e7010.

  •  Xin-Lin Zhang, Qing-Qing Zhu, Li-Na Kang, Xue-Ling Li, and Biao Xu.Mid- and Long-Term Outcome Comparisons of Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Metallic Stents: A Systematic Review and Meta-analysis. Annals of Internal Medicine. 2017，167（9）：642-654.

  •  Xin-Lin Zhang, Biao Xu.Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement. Annals of Internal Medicine. 2017，166（8）：605.

  • Guannan Li, Jun Xie, Jianzhou Chen, Ran Li, Han Wu, Xinlin Zhang, Qinhua Chen, Rong Gu , Biao Xu.Syndecan-4 deficiency accelerates the transition from compensated hypertrophy to heart failure following pressure overload. Cardiovascular Pathology. May-June，2017 Volume 28，Pages74–79.

  • Guannan Li, Jianzhou Chen, Xinlin Zhang, Guixin He, Wei Tan, Han Wu, Ran Li,Yuhan Chen, Rong Gu, Jun Xie & Biao Xu.Cardiac repair in a mouse model of acute myocardial infarction with trophoblast stem cells. Scientific Reports. 2017 Mar 15;7:44376.

  •  Jun Xie, Yuhan Chen, Chuanxian Hu, Quanhua Pan, Bingjian Wang, Xueling Li, Jin Gengand Biao Xu.Premature senescence of cardiac fibroblasts and atrial fibrosis in patients with atrial fibrillation. Oncotarget. 2017, 8(35)：57981-57990.

  • Xueling Li, Jin Geng, Yuhan Chen, Fu Chen, Chen Liu, Qiwen Xu, Jinxuan Zhao,Jiaxin Hu, Jun Xie, Biao Xu.Exposure to particulate matter induces cardiomyocytes apoptosis after myocardial infarction through NFkB activation. Biochem Biophys Res Commun. 2017 Jun 17;488(1):224-231.

  •  Jun Xie, Suhui Zhu, Qing Dai, Jianrong Lu, Jianzhou Chen, Guannan Li, Han Wu, Ran Li, Wei Huang, Biao Xu, Wei Xu,.Oncostatin M was associated with thrombosis in patients with atrial fibrillation. Medicine. (2017) 96:18(e6806)

  •  Gui-xin He,Jun XieHao,JiangWeiTan,Biao Xu.Effects of Qishen Yiqi Dripping Pills () in reducing myocardial injury and preserving microvascular function in patients undergoing elective percutaneous coronary intervention: A pilot randomized study. Chin J Integr Med.2017 May 3.

  •  Wen Lu,Jun Xie, Rong Gu,and Biao Xu.Expression of integrin-linked kinase improves cardiac function in a swine model of myocardial infarction. Exp Ther Med. 2017 May;13(5):1868-1874

  •  Jin Geng, Yanchun Zhang, Bingjian Wang, Jun Xie, Biao Xu, Ju Li.Glycosylated hemoglobin levels and clinical outcomes in nondiabetic patients with coronary artery disease. Medicine (Baltimore). 2017 Apr; 96(17): e6784.

  •  Yang Li, Jing-Jing Yang, Su-Hui Zhu, Biao Xu, Lian Wang.Long-term efficacy and safety of carotid artery stenting versus endarterectomy: A meta analysis of randomized controlled trials. PLOS ONE. 2017 Jul 14;12(7):e0180804.

  •  Jun Xie,Ran Li,Han Wu,Jian-Zhou Chen,Guan-Nan  Li,Qin-Hua Chen,Zhong-Hai Wei,Gui-Xin He,Lian Wang,Albett Ferro,Biao Xu. Advanced Glycation Endproducts Impair Endothelial Progenitor Cell Migration and Homing via Syndecan 4 Shedding. Stem Cells. 2017,35（2）:522-531.

  •  Xin-Lin Zhang, Biao Xu.Everolimus-Eluting Bioresorbable Scaffold Versus Everolimus-Eluting Metallic Stents. Annals of Internal Medicine. 2016 Dec 6;165(11):829. doi: 10.7326/L16-0419.

  •  Jiang C, Zhu W, Yan X, Shao Q, Xu B, Zhang M, Gong R.Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease via targeting GSK3β. Sci Rep. 2016 Nov 18;6:36698. doi: 10.1038/srep36698.

  •  HanWu, Zheng Chen, Jun Xie, Li-Na Kang, LianWang, and Biao Xu.High Mobility Group Box-1: A Missing Link between Diabetes and Its Complications. Mediators Inflamm. olume 2016, Article ID 3896147, 11 pages.

  •  Han Wu,Zhen-Qiang Sheng,Jun Xie,Ran Li,Liang Chen,Guan-Nan Li,LianWang,and Biao Xu.Reduced HMGB 1-Mediated Pathway and Oxidative Stress in Resveratrol-Treated Diabetic Mice: A Possible Mechanism of Cardioprotection of Resveratrol in Diabetes Mellitus. Oxid Med Cell Longev. Volume 2016, Article ID 9836860, 10 pages.

  •  Zhonghai Wei,Jun Xie,Kun Wang,Lina , Qing ,Jian , Biao .Comparison of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graft in Aged Patients With Unprotected Left Main Artery Lesions.. International Heart Journal. 2016,57(6):682-688.

  •  Li L, Lopes J, Zhou JY, Xu B. Integrating Medical Simulation Into the Physician Assistant Physiology Curriculum. J Physician Assist Educ. 2016 Dec;27(4):156-161.

  •  Ran Li,Han Wu ,Jun Xie ,Guannan Li ,Rong Gu ,Lina Kang ,Lian Wang,Biao Xu.Syndecan-4 regulates the bFGF-induced chemotactic migration of endothelial cells. J Mol Histol. 2016 Oct;47(5):503-9. doi: 10.1007/s10735-016-9693-0.

  •  Li SN, Zhang XL, Cai GL, Lin RW, Jiang H, Chen JZ, Xu B,Huang W.Prognostic Significance of Frontal QRS-T Angle in Patients with Idiopathic Dilated Cardiomyopathy. Chin Med J (Engl). 2016 Aug 20;129(16):1904-11. doi: 10.4103/0366-6999.187844.

  •  24. Zhonghai Wei, Jie Song, Xuebing Feng, Ning Zhang, LianWang, Biao Xu. Reversal of cardiac remodeling after treatment of IgG4 related cholangitis.International Journal of Cardiology, 2016,222:257–259.

  • Zhonghai Wei, Xinlin Zhang, Han Wu, Jun Xie, Qing Dai,Lian Wang, Biao Xu. A meta-analysis for efficacy and safety evaluation of transcatheter left atrial appendage occlusion inpatients with nonvalvular atrial fibrillation.Medicine, 2016,95(31):e4382

  •  Geng J, Ye X, Liu C, Xie J, Chen J, Xu B, Wang B.Outcomes of off- and on-hours admission in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: A retrospective observational cohort study. Medicine (Baltimore). 2016 Jul;95(27):e4093. doi: 10.1097.

  • , , , , , .Amlodipine Ameliorates Ischemia-Induced Neovascularization in Diabetic Rats through Endothelial Progenitor Cell Mobilization. Biomed Res Int. 2016;2016:3182764. doi: 10.1155/2016/3182764.

  • , , , , , , .Tanshinone IIA Protects Against Folic Acid-Induced Acute Kidney Injury..Am J Chin Med2016;44(4):737-53.

  •   Han Wu, Liang Chen, Jun Xie, Ran Li, Guan-nan Li, Qin-Hua Chen, Xin-Lin Zhang, Li-Na Kang and Biao Xu.Periostin expression induced by oxidative stress contributes to myocardial fibrosis in a rat model of high salt-induced hypertension. Mol Med Rep. 14: 776-782, 2016.

  •  Li J, Li Y, Xu B, Jia G, Guo T, Wang D, Xu K, Deng J, Han Y.Short-term rosuvastatin therapy prevents contrast-induced acute kidney injury in female patients with diabetes and chronic kidney disease: a subgroup analysis of the TRACK-D study. J Thorac Dis. 2016 May;8(5):1000-6. doi: 10.21037/jtd.2016.03.26.

  • Zhonghai Wei, Lian Wang, Jun Xie, Wei Huang, Lina Kang, Kun Wang, Jingmei Zhang, Jie Song, Biao Xu.The therapeutic effect of rotational atherectomy with implantation of drug eluting stent in heavily coronary calcified patients. Journal of Geriatric Cardiology,2016,13:233-238

  •  Xin-Lin Zhang,Li Zhu,Zhong-HaiWei, Qing-Qing Zhu,Jian-Zhong Qiao, Qing Dai, Wei Huang, Xiao-Hong Li, Jun Xie, Li-Na Kang, LianWang, and Biao Xu.Comparative Efficacy and Safety of Everolimus-Eluting ioresorbable Scaffold Versus Everolimus-Eluting Metallic Stents. Annals of Internal Medicine. 2016 Jun 7;164(11):752-63. doi: 10.7326/M16-0006.

  • , , , , , , , . Syndecan-4 shedding impairs macrovascular angiogenesis in diabetes mellitus. Biochem Biophys Res Commun. 2016 May 20;474(1):15-21. doi: 10.1016/j.bbrc.2016.03.112.

  •  Guixin He,Wei Tan, BingjianWang, Jianzhou Chen, Guannan Li, Suhui Zhu,Jun Xie, Biao Xu.Increased M1 Macrophages Infiltration Is Associated with Thrombogenesis in Rheumatic Mitral Stenosis Patients with Atrial Fibrillation.PloS One. 2016 Mar 1;11(3):e0149910. doi: 10.1371/journal.pone.0149910.

  •  Qiaoling Li, Jun Xie, BingjianWang, Ran Li, Jian Bai, Liang Ding, Rong Gu,LianWang, Biao Xu.Overexpression of microRNA-99a Attenuates Cardiac ypertrophy. PLoS One. 2016 Feb 25;11(2):e0148480.


    • 承担科研项目[项目负责人]

    2020年，基于抗炎策略的间充质干细胞外泌体治疗急性心梗心肌缺血再灌注损伤的研究，国家自然科学基金-面上项目，82070366

    2017年，江苏省医学重点学科，江苏省卫生和计划生育委员会

    2016年，经皮梗死血管综合血栓清除治疗急性心梗的临床研究，江苏省科技厅社会发展项目（重大项目）BE2016607

    2015年，PAK3在心肌肥大中的作用和机制研究，国家自然基金面上项目，81470371

    2014年，心肌细胞再生的基础和应用研究，南大六合彩论坛 省分子医学重点实验室

    2013年，南京心血管病临床医学中心，南京市卫生和计划生育委员会

    2013年，Cdx2+胎盘干细胞移植治疗急性心肌梗塞的实验研究，国家自然科学基金面上项目，81270281

    2012年，急性心肌梗死的规范化诊治的流程和新技术的建立及应用，江苏省临床医学科技专项，BL2012014

    2011年，转ILK基因治疗终末期心脏病，江苏省卫生厅医学领军人才和领军团队，LJ201153

    2011年，转ILK基因治疗终末期心脏病的基础研究，南大中央高校重点项目，1114021402

    2010年，心肌高表达ILK对心力衰竭心功能的影响及其机制研究，国家自然科学基金面上项目，81070195

    2009年，移植转染ILK基因的干细胞治疗急性心梗疗效和机制研究，省科技厅自然基金，BK2009036

    2008年，糖尿病组织缺血后血管新生障碍的基础和临床研究，科技局国际合作，200801121

    2007年，糖尿病血管新生障碍的基础和临床研究，卫生厅兴卫工程，RC2007001

    2006年，心脏干细胞的基础和临床研究，人事厅六大人才高峰项目

    2006年，心脏干细胞的基础和临床研究，科技局社会发展，200601057

    2004年，糖尿病动脉粥样硬化斑块不稳定性增加的分子机制，省科技厅自然基金，BK2004083

    2003年，急性心肌梗塞血管内超声消融的基础和临床研究，卫生局重点项目，ZKX0316

    获奖情况

    新一代准分子激光经皮冠脉斑块消蚀术（2020年，江苏省医学新技术一等奖，排名第一）

    新一代准分子激光经皮冠脉斑块消蚀术（2019南京市卫生与健康新技术特等奖，排名第一）

    心力衰竭发生发展的分子靶点探索和应用基础研究（2019年江苏省科技进步二等奖，排名第一））。

    利用系统评价及荟萃分析方法探索并解决心血管介入及药物治疗临床问题（2019年，江苏医学科技一等奖，排名第一）。

    左室重构的分子机制和干预靶点的研究（2018年，中华医学科技奖三等奖，排名第一）

    左室重构的分子机制和干预靶点的研究（2017年，江苏省医学科技奖一等奖 ，排名第一）。

    主动脉内球囊反搏支持下联合血管内超声指导行左主干钙化病变旋磨及药物支架植入术（2017年，江苏省医学新技术一等奖，排名第一）。

    促进EPC动员治疗心肌梗死的临床新技术应用（2014年，江苏省医学新技术引进一等奖，排名第一）。

    糖尿病血管功能障碍的基础及临床研究（2013年，江苏医学科技奖一等奖，排名第一）。

    糖尿病血管功能障碍的基础及临床研究（2013年，江苏省科技进步奖三等奖，排名第一）。

    糖尿病血管功能障碍的基础及临床研究（2013年，南京市科技进步奖二等奖，排名第一）。